Effect of different drying methods on content of index components of Xiasangju granules

ABSTRACT: Objective: To optimize the drying method of Xiasangju granule extract.

Methods: the extract of xisanju chrysanthemum granules was extracted and concentrated, and the extract was divided into 3 parts. Each part was dried by vacuum, spray drying and microwave drying equipment. The dried extract powder was extracted by chlorogenic acid, rosmarinic acid and Mongol glucoside by HPLC. Content determination.

microwave drying equipment

Chromatographic conditions: The column was Waters Symmetry Shield RP18 (5 micron, 4.6 m m x 250.0 m m), and the mobile phase gradient elution was acetonitrile (A) - (volume fraction) 1.0% acetic acid solution (B). The flow rate was 0.9 mL.m. In-1, column temperature 35 C, detection wavelength 320 nm.

Conclusion: the method can be used to evaluate the different drying methods of Xia Sang Ju granules. The effects of 3 drying methods on the index components are vacuum drying, microwave drying and spray drying. 

Xia Sang Ju microwave drying