Application of Microwave Technology in Pharmaceutical Field

ABSTRACT: Starting from the definition and characteristics of microwave and its advantages in the production of traditional Chinese medicine extracts, the application of microwave-assisted extraction, microwave drying equipment and microwave sterilization technology in the field of medicine was studied, which promoted the pharmaceutical industry, especially the traditional Chinese medicine industry, to achieve the goals of energy saving, consumption reduction and environmental protection, and played a potential role in improving yield, quality and cost reduction.

microwave drying equipment 

Key words: microwave; extraction; drying; sterilization; energy saving; environmental protection; microwave drying of traditional Chinese medicine

Our country has a vast territory, spanning from tropical zone to cold temperate zone, with abundant plant resources. The Chinese culture accumulated over 5000 years and the vast medical books left by our ancestors are the unique conditions for the development of Chinese medicine. The role of traditional Chinese medicine in the prevention and treatment of common diseases, frequently-occurring diseases, chronic diseases, difficult diseases and major infectious diseases has been further highlighted, and has been widely recognized by the international community.

microwave drying of traditional Chinese medicine 

Distribution Model of Temperature and Moisture in Microwave Drying of Activated Rice

ABSTRACT: By establishing the mass and heat transfer model of continuous microwave drying of activated rice, the temperature and moisture content distribution in the microwave dryer of activated rice were obtained. The temperature and moisture models of activated rice were validated under the conditions of microwave intensity of 1.16, 2.75 and 4.34 W/g, and the correctness of the heat and mass transfer model was confirmed.

microwave dryer

The results of simulation and measurement show that the microwave power can be controlled when the temperature rises slowly at the end of the continuous microwave dryer, and the energy consumption of microwave drying can be reduced. After the drying stage, the temperature inside and outside of the active rice material can be balanced, the drying effect is more uniform and the drying quality can be guaranteed. The research has guiding significance for microwave heating technology and control of active rice.

microwave drying of active rice

Effect of microwave drying on the content of Codonopsis alkynoside in Codonopsis pilosula

ABSTRACT: OBJECTIVE: To investigate the effect of microwave drying equipment on the content of Codonopsis alkynoside in Codonopsis pilosula so as to provide basis for scientific evaluation and effective control of its quality. METHODS: HPLC, gradient elution and ultrasonic extraction were used. The chromatographic conditions were as follows: Kromasil C18 column (4.6 mm *250 mm, 5 micron), flow rate: 1.0 mL/min, detection wavelength: 267 nm, column temperature: 25 C, mobile phase: acetonitrile-0.05% phosphoric acid gradient elution system.

microwave drying equipment

RESULTS: The content of Codonopsis glycoside was higher in different microwave time (5 min, 5.5 min, 6 min, medium fire) and 25% honey-baked Codonopsis pilosula microwave for 5 min under the same conditions.

CONCLUSION: Different microwave time can affect the content of Codonopsis alkynoside in Codonopsis pilosula. The content of Codonopsis alkynoside in Codonopsis pilosula is higher when it is roasted with 25% honey and microwave for 5 minutes. Meanwhile, the determination of Codonopsis alkynoside in Codonopsis pilosula by HPLC is simple, reliable and reproducible. It can be used as an effective method for quality control of Gansu genuine medicinal material Codonopsis

Codonopsis pilosula microwave drying 

Effect and evaluation of different drying methods on multi-functional components in mint

[Abstract] GC-MS and UPLC-TQ-MS techniques were used to analyze and evaluate the chemical composition and content changes of two monoterpenes, four phenolic acids and five flavonoids in Mentha peppermint by different drying methods, and the effects of drying methods on their chemical composition were investigated. TOPSIS comprehensive analysis method was used to evaluate the chemical composition of Mentha peppermint, which provided a basis for the determination of appropriate drying methods.

microwave drying equipment

The results showed that microwave drying equipment had the greatest influence on the content of menthol, caffeic acid and rosmarinic acid, followed by chlorogenic acid and geranin-7-O-glucoside. At the same temperature, the retention of active ingredients by hot air drying was better than that by microwave drying and infrared drying. The retention of total active ingredients by low temperature drying (40-45 C) was significantly higher than that by high temperature drying (60-70 C). The total amount of phenolic acids in the treated samples was significantly higher than that in the untreated samples, showing a certain degree of enzymatic activity.

Mint microwave drying

Effect of three drying methods on volatile oil of turmeric

ABSTRACT: OBJECTIVE To analyze the effects of sun drying, blast drying and microwave drying equipment on the volatile oil of Curcuma longa Wenyujin Rhizoma Concisum. METHODS The volatile oil was extracted by steam distillation after Curcuma Curcuma was dried, analyzed and identified by GC-MS, and then the relative contents of each component were determined.

microwave drying equipment

Results Twenty-six components were identified in volatile oil of sun dried products, 29 in blast dried products and 28 in microwave dried products. The relative content of zedoary Dione was the highest among the three dried products, especially in sun dried products, but it did not contain neozedoary dione.

CONCLUSION After drying by three methods, the components of volatile oil from Curcuma longa L. tablets are basically the same, but the relative contents are different. Under the conditions of blast drying and microwave drying, the complex isomerization of curcumadione and neocurcumadione may occur, which changes the relative content of curcumadione.

microwave drying of traditional Chinese medicine

Effect of Microwave Drying Technology on Thermosensitive Components of Radix Notopterygii

ABSTRACT: Objective: To investigate the effect of microwave drying equipment on the content of volatile oil in Radix Notopterygii after drying, and to compare the effects of different drying methods on the overall chemical composition of Radix Notopterygii.

microwave drying equipment 

METHODS: The determination methods under the item of Qianghuo in Chinese Pharmacopoeia 2015 were adopted. CONCLUSION: Microwave vacuum drying can not only ensure drying efficiency, but also fully retain the thermosensitive components, and has no effect on the whole components of Radix Notopterygii.

Key words: microwave drying Radix Notopterygii; volatile oil; characteristic Atlas

Notopterygi-um inchum Ting ex H.T.Chang, or Notopterygi um franchetii H.de Boiss, a perennial herb of Umbelliferae, has the functions of dispelling cold, dispelling wind, removing dampness and relieving pain. The main physiological active ingredients of Notopterygi um inchum Ting ex H.T.Chang or Notopterygi um franchetii H.de Boiss.

microwave drying Radix Notopterygii 

Effects of Different Drying Methods on Main Chemical Components in Polygala tenuifolia Tube and Root

ABSTRACT: OBJECTIVE To investigate the effects of five drying methods, i.e. sun drying, shade drying, hot air drying (40, 50, 60, 70 C), microwave drying and freeze drying, on the main chemical constituents of Polygala tenuifolia and its roots. METHODS The components and contents of polygalone III, 3,6’-dimustinoyl sucrose, polygallic acid, polygalactoside and polygalactoside in Polygala tenuifolia were determined by HPLC with different drying methods. The data were analyzed by one-way ANOVA and TOPSIS.

Microwave Drying Equipment

Result There were differences in the optimum order of drying methods between Radix Polygalae and its roots. The order of the effects of different drying methods on the active ingredients was Microwave Drying Equipment > 60 C hot air drying > 50 C hot air drying > 70 C hot air drying > freeze drying > 40 C hot air drying > shade drying > sun drying. In Radix Polygalae, the order of different drying methods was microwave drying > 60 C hot air drying > freeze drying. Shade drying > sun drying > 50 C hot air drying > 40 C hot air drying > 70 C hot air drying > freeze drying.

microwave drying of traditional Chinese medicine