ABSTRACT: Objective: To compare the effects of different microwave drying equipment on the content of baicalin magnesium salt, to optimize the best drying method of baicalin magnesium salt and to study its anti-inflammatory effect. Methods: Freeze dryer, microwave dryer and drying box dryer were used to dry baicalin magnesium salt. The best drying method was to determine the content of baicalin magnesium salt after drying by HPLC. At the same time, animal inflammation model was constructed and the swelling degree was observed.
Result: The content of frozen dried baicalin magnesium salt was 69.2%, microwave dried baicalin magnesium salt was 65.3%, and drying box dried baicalin magnesium salt was 59.8%. The anti-inflammatory effect of baicalin magnesium salt was better than baicalin. CONCLUSION: Freeze-drying method was used to dry Baicalin Magnesium Salt with high content.
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