ABSTRACT: OBJECTIVE To optimize the drying process of Qiwei Shuanghua Chaihu capsule extract. Methods taking dry paste characteristics, yield, hygroscopicity and chlorogenic acid transfer rate as evaluation indexes, three drying methods, vacuum drying, microwave drying equipment and spray drying, were investigated.
Results the transfer rates of chlorogenic acid in dry paste prepared by vacuum drying, microwave drying and spray drying were 82.5%, 89.6% and 92.3% respectively, and the dry paste quality was 17.66mg. G - 1.
19.89 mg.g-1 and 20.71 mg.g-1 respectively.
Conclusion spray drying time is the shortest, the appearance characteristics of the obtained materials are the best, and the transfer rate of the index components is the highest. It is the best drying method for the seven flavored double flower Bupleurum extract.
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